Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Sodium Channel - QX-222 chloride

QX-222 chloride

CAS No. 5369-00-6

QX-222 chloride ( QX 222; Lidocaine N-Methyl Hydrochloride )

Catalog No. M27693 CAS No. 5369-00-6

QX222 is a sodium channel blocker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 Get Quote
10MG 58 Get Quote
25MG 111 Get Quote
50MG 205 Get Quote
100MG 335 Get Quote
200MG 494 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    QX-222 chloride
  • Note
    Research use only, not for human use.
  • Brief Description
    QX222 is a sodium channel blocker.
  • Description
    QX222 is a sodium channel blocker.(In Vitro):Compared with μ1-WT (WT, 14.2±1.6% block, n = 8; Y401C, 45.2±3.6% block, n = 9; P < 0.001), μ1 IP-Loop to Heart Sequence (μ1-Y401C) results in a significant block twelve minutes after external application of 500 μM QX222 chloride.(In Vivo):Intravenous infusion administration of 10 mg/kg QX-222 chloride for 7 days reverses spinal nerve ligation (SNL)-induced thermal hypersensitivity and induced antinociception in sham-operated rats.
  • Synonyms
    QX 222; Lidocaine N-Methyl Hydrochloride
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    c-Src
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5369-00-6
  • Formula Weight
    220.3
  • Molecular Formula
    C13H20N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1cccc(C)c1\N=C(/[O-])C[N+](C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.O'Malley DP, et al. Discovery of Pyridazinone and Pyrazolo[1,5-a]pyridine Inhibitors of C-Terminal Src Kinase. ACS Med Chem Lett. 2019 Sep 25;10(10):1486-1491.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Tocainide

    Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.

  • PF-06305591

    PF-06305591 (PF06305591) is a potent, highly selective selective NaV1.8 blocker with IC50 of 15 nM, displays no significant activity against other sodium channel subtypes, K+ channels and Ca2+ channels.

  • Dimethyl lithosperma...

    Dimethyl lithospermate B is a selective Na+ channel agonist.

Sign In Join Free